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If you are looking for the companion files to the text click here.
To read the foreword for the text written by Gary S. Kath, Senior Manager of the BioElectronics Laboratory of Merck & Co in Rahway, NJ click here.
To look at the Table of Contents for the Text click here.
To Purchase the Text Click here.
This text will only improve if the readers give suggestions for improvement and report corrections, bugs, and errors. Full credit will be given to those whose corrections, ideas, and suggestions are incorporated in the second edition. To provide feedback on the text click here.
Unlike many texts which are theoretical in content or most standard computer books which are listing of commands, properties, and methods; this text is more along the lines of an interactive tutorial. For example, the standard run of the mill text on Excel or VBA programming will discuss the features available in Excel and maybe some basic VBA programming concepts (like how to use a loop), but the user has no real sense of how to put together a practical application. My text shows the user how to automate the analysis of a sample set of data and put together a laboratory report in a spreadsheet type of format. The reader is then left knowing how the sample application works, and can adjust it to suit whatever needs their organization may have. Putting together an application can be problematic for any user because of all the little quirks and glitches one will encounter during the process. Similarly, for Visual Basic, instead of showing basic constructs which one can get from any number of texts, this text shows how to build a device driver for a Kloehn syringe and how to interface with Keithley Metrabyte I/O cards. There are numerous books on electronics but this text shows how to utilize some basic methods found in many texts such as low pass filtering, comparators, and peak detection to create viable instrument interfaces. A section on the supercharged spreadsheet package Origin demonstrates how to automate curve fitting of laboratory data. For those involved in HPLC work, a section on Agilent Chemstation software shows everything from how to automate the exporting of laboratory data, to peak selection, and utilizing Chemstation Objects, Registers, and Tables. The true power of the text is that it shows the user what pitfalls they are likely to encounter when trying to automate such a process. By explaining the mechanics of the examples in the text, the user develops a thought process which enables them to solve their own unique automation problems.
This site also serves as a central repository for useful nonproprietary information related to Pharmaceutical Laboratory Automation which has been approved for release into the public domain by its respective authors and owners. On this site one will find information relating to Assay development in areas such as solubility, pKa, and ELogD. Computer programming in Visual Basic, Visual Basic for Applications, Origin, and Agilent HPLC Chemstation Macro Programming is also covered. Numerous presentations are available on topics such as Chris Lipinski’s “Rule of 5”, Experimental LogD, and Assay Development. Hard to find information on reverse engineering laboratory instruments, electronics for laboratory automation, and software/hardware interfacing is also provided.
The author of this site has worked for Pfizer Global Research and Development for the past eight years in areas such as Medicinal Chemistry, Physical Measurements, and Molecular Properties. Prior to this, the author worked as a contract civilian electrical engineer for the United States Navy providing testing and fabrication of hybrid analog preamplifiers for towed arrays, and designing high speed digital communication cards for the Navy’s New Sonar Intercept System (NSIS).
This site was built using Net Objects Fusion 7.0. In all probability it will be the last site I build using Fusion. If you would like to find out why click here.
I started running Linux at home, maybe you should be too.
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