Pharmaceutical Laboratory Automation

This page serves as a repository for some great presentations on solubility given at various conferences by Chris Lipinski  or Brian Bissett of the Molecular Properties Group at Pfizer Global Research & Development in Groton, CT.

Bissett - “Development of Pfizer’s 3rd Generation Turbidimetric Solubility Assay”
Bissett - “Platereader Solubility Assay
Lipinski - “Chemical Property Optimization for Proof of Bioavailability”
Lipinski - “Solubility Screening in an Early Drug Discovery Setting”
Lipinski - “Visualization of Results from the Rule of 5”
Lipinski - “Drug Structures and Properties, Past and Present. Can We Design Drugs with Beautiful Properties?”
Lipinski - “Absorption Prediction: Computational Alerts for Potential Absorption Problems”
Lipinski - “Changes in Drug Physicochemical Properties Arising from Combinatorial Chemistry and High Throughput Screening: New Instrument Opportunities.”
Lipinski - “Computational Approach to Potential Absorption Problems: Analysis of Human Data”
Lipinski - “Changes in the Profiles of Drug Properties: An Experimental, Computational and Informatics Perspective”